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Healing

Thymosin Alpha-1

≥99.6% HPLC Verified Purity

CAS Number62304-98-7

Molecular Weight3108.3 Da

Molecular FormulaC₁₂₉H₂₁₅N₃₃O₅₅

Storage−20°C · Lyophilized

$55.00/ vial

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RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.

What is Thymosin Alpha-1?

Thymosin Alpha-1 is a synthetic version of a naturally occurring thymic peptide originally isolated from thymosin fraction 5. With the molecular formula C₁₂₉H₂₁₅N₃₃O₅₅ and a molecular weight of 3108.3 g/mol (CAS: 62304-98-7), Thymosin Alpha-1 is a 28-amino acid peptide representing the N-terminal acetylated fragment of prothymosin alpha.

Amino Acid Sequence:Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn

Classification: Thymic PeptideTLR ReceptorsT-Cell Receptors

Specifications

CAS Number	62304-98-7
Molecular Formula	C129H215N33O55
Molecular Weight	3108.3 Da
Purity	≥99.6% (HPLC verified)
Form	Lyophilized powder
Storage	−20°C · Lyophilized

Published Research

Romani et al. (2006) characterized Thymosin Alpha-1's interactions with Toll-like receptors and dendritic cell activation markers in vitro (PMID: 16683274).

PMID: 16683274VERIFY PMID

King et al. (2008) reviewed Thymosin Alpha-1's receptor binding properties and intracellular signaling pathways in immune cell models (PMID: 18423086).

PMID: 18423086VERIFY PMID

Mechanism of Action

TLR Signaling

MyD88-dependent pathway

Thymosin Alpha-1 interacts with Toll-like receptors, activating MyD88-dependent signaling and NF-κB translocation in immune cell cultures (PMID: 16683274).

T-Cell Activation

TCR signaling enhancement

Research indicates the peptide enhances T-cell receptor signaling and T-cell differentiation markers in lymphocyte cultures (PMID: 18423086).

Storage & Handling

Temperature:-20°C for long-term storage

Light Sensitivity:Protect from direct light

Stability Duration:Stable for 24 months when stored properly

Acetylated at the N-terminus for enhanced stability.

Related Compounds

Thymalin TB-500 BPC-157

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

Research Catalog

High-purity, structurally verified peptide sequences for advanced laboratory and pre-clinical applications.