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Healing

TB500

≥99.5% HPLC Verified Purity

CAS Number77591-33-4

Molecular Weight4963.5 Da

Molecular FormulaC₂₁₂H₃₅₀N₅₆O₇₈S

Storage-20 °C, lyophilized

$50.00/ vial

RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.

What is TB-500?

TB-500 (Thymosin Beta-4 Fragment) is a synthetic 43-amino acid peptide representing the active region of the naturally occurring Thymosin Beta-4 protein. With the molecular formula C₂₁₂H₃₅₀N₅₆O₇₈S and a molecular weight of 4963.5 g/mol (CAS: 77591-33-4), TB-500 is the research designation for the peptide fragment containing the primary bioactive sequence of the parent protein.

Amino Acid Sequence:

Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH

Classification: Actin-Binding Peptide FragmentActin CytoskeletonG-Actin Binding

Specifications

CAS Number	77591-33-4
Molecular Formula	C212H350N56O78S
Molecular Weight	4963.5 Da
Purity	≥99.5% (HPLC verified)
Form	Lyophilized powder
Storage	-20 °C, lyophilized

Mechanism of Action

Actin Cytoskeleton

G-actin sequestration

TB-500 binds to monomeric G-actin, regulating actin polymerization and cytoskeletal dynamics in cell culture models.

Cell Migration

Integrin signaling

Published studies demonstrate effects on cell motility through interactions with integrin receptors and focal adhesion dynamics.

Storage & Handling

Temperature:-20°C for long-term storage

Light Sensitivity:Protect from direct light

Stability Duration:Stable for 24 months when stored properly

Store the lyophilized powder sealed at −20°C, protected from light and moisture, and minimize temperature fluctuations to preserve compound integrity during long-term storage.

Related Compounds

BPC-157 GHK-Cu Thymosin Alpha-1

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.